Californication.
I kinda enjoyed the first season, but something changed with the 2nd season, and I just started thinking "Why am I watching these assholes?". Literally every character on the show was an asshole, and not the entertaining kind.
Also, I enjoyed the first season of American Horror Story, but season 2 was a bunch of nonsense that threw away a cohesive plot in favour of jam-packing every asylum cliche you could imagine with a bunch of stuff that is never explained, and season 3 was so terrible that I stopped watching in the middle of the first episode - it actually seemed like it was written over the weekend. I'm done with that show. Too bad, I wanted to like it.
Other shows that I attempted but could not get into:
Rescue Me - More assholes, not the entertaining kind
Big Bang Theory - Painfully unfunny. Bernadette is hot doe. Would burgle.
Community - Season 1 was good, but after that, just a bunch of nonsense. Like it was written by Dennis Miller's hipster son.