I would say though that whilst significant lobbying obviously exists my guess is that its very much a two way thing, that is I suspect there is a very strong pro Israeli culture in US foreign politics, looking at Biden's background it seems pretty clear he's been part of it since the 70's. Its not just the Israeli's buying influence but working in very fertile ground with IMHO groups like AIPAC often being viewed as a more effective way to silence dissenters, looks better for them to go after someone like Llhan Omar that it does for the Pro Israeli Dems to do it themselves.
Backing Israel against US interests I don't think is just lobbying basically but rather the result of political culture in the US, when certain viewpoints become basically unmentionable(Criticism of Israel) in mainstream political/media culture it ends up with poor decisions being made even if you look at things purely in amoral realpolitik.
Its often talked about that US foreign policy is self serving but a lot of the criticism of Neoliberialism is that its actually ideological, the ideology at a base level maybe self serving(such as anti communist views in the mid 20th century) but those making the decisions are often true believers in it.
