1996 Ohio St. Vs michigan- probably the best collection of talent on the roster from top to bottom in school history and true to form for the Cooper era, assholes were puckered tight enough to turn a lump of coal into a diamond. A Shawn Springs slip on a slant and a national title down the shitter.
2007 national title game tOSU vs Florida- undefeated and un characteristically high powered on offense for a Tressel team and Troy Smith goes on the Awards circuit and hits every all you can eat buffet in 10 states to bloat up to the size of your average D1 nose tackle before the biggest game of his career. All hope quickly evaporated after Ted Ginn returned the opening kickoff for 6 only to have some dumb fuck jump on him in the end zone and put him out for the game. The rout was on after that.
2012 Gator Bowl vs Florida- not because I really give two shits about losing the Gator Bowl after a season that would make Rich Rodriguez blush, but because the game was even played in the first place. Had the morons making the decisions had the sense to self impose a bowl ban, instead of rewarding the fucktards responsible for the mess with a bowl game, we would have had a gift national title the following year. Instead, we get an undefeated season with no bowl game in a season where 5 or more teams would have beat unbeaten Notre Dame for the title.