Yes. Orton (they even changed the rules -afterwards) and Lesnar (another rule change) come to mind when rules were blatantly broken regarding drug tests. Cena has never popped and he ain’t doing tests. Undertaker has said that he ain’t pissing into a cup EVER. Those are Jones level stars. But one of those level popped for a test, Roman Reigns, the chosen one for the future of WWE. Maybe he was Conor level because the boss absolutely loved him.
BUT I don’t think they ever moved an event from a city. They once got fucked over an arena (the owner told them he’s cancelling because the local basketball team need it) and they went to a new place in the same city and really ripped the owner for doing that shit in a segment on tv. And when shit happens because injury or shit, they usually compensate the fans by UPPING the card in the same place.
So say WWE was UFC, Jones popped or injury then they would keep the place and put Undertaker and the Rock in. Or maybe saying GSP and Conor would be more appropriate.