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Personally, I would not follow Lyle McDonald's exercise recommendations. I would do an easy to follow routine that builds up a solid strength foundation. The benefits from weightlifting for weight loss don't come primarily from glycogen depletion, they come from the genetic changes involved in building muscle, inducing beneficial neural adaptations, and exposure to physiological stress.
I would look at programs that are listed in the S&C FAQ like Starting Strength, Madcow or Stronglifts. Your weight loss will more than likely continue with or without weightlifting, but if you're going to spend the time in the gym you may as well be building a foundation for the future, not wasting time doing Lyle's routine that's full of leg presses, leg curls, crunches and bicep work.
I would look at programs that are listed in the S&C FAQ like Starting Strength, Madcow or Stronglifts. Your weight loss will more than likely continue with or without weightlifting, but if you're going to spend the time in the gym you may as well be building a foundation for the future, not wasting time doing Lyle's routine that's full of leg presses, leg curls, crunches and bicep work.