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For self defence when you have no option, you should look at the rules of MMA and see what is banned and then practise exactly that.
That said I have grappled with a guy who was that much heavier but only about 2 inches taller I did well in a pure BJJ sense. Basically he took me down, gassed himself and then got guiloteened.
But a guy that much bigger who has trained anything near as much as me would just destroy me so I would really need to know why I can't just run.
What I was going to say but I would mention the eye pokes.
That said I have grappled with a guy who was that much heavier but only about 2 inches taller I did well in a pure BJJ sense. Basically he took me down, gassed himself and then got guiloteened.
But a guy that much bigger who has trained anything near as much as me would just destroy me so I would really need to know why I can't just run.
kicking them in the nuts is your best shot so I would go with krav maga.
What I was going to say but I would mention the eye pokes.