The vast majority of supplements are for the most part useless. The large meta-analyses I’ve seen for multivitamins and isolated vitamins show pretty ambiguous results. Same for minerals. It seems to me that in populations where there isn’t some sort of mineral/vitamin deficiency, it’s uncertain whether these things taken in isolation make any difference. And separating the effect of the vitamin itself from the diet containing the vitamin is complicated as well. IMO if you have a healthy diet and normal blood levels of this stuff, or no symptoms of deficiency or disease, it’s uncertain whether these things would make any difference.
Creatine is legit and has been proven to enhance performance on average over and over again. Keyword: on average. Some people seem not to respond to it. But if you care about your athletic performance, it’s very low risk for a possible (even if small) benefit. Others like beta alanine and citruline malate seem to have strong legitimate evidence for performance enhancement as well, but similarly, the effects are overall small.
As for all those mushrooms and herbs I haven’t looked into them because I’m too lazy, but I assume that if they did anything ground breaking I probably would’ve heard of it. I follow a few people who review these studies and check every once in a while what they’re saying and kind of delegate on them to do the research. I’ll invest that money in healthy food for now unless I hear of anything groundbreaking.
Things like peptides, BPC157 and TB500 and so on, aren’t approved yet for human use by any large drug administration body, and they are considered experimental drugs that haven’t gone through large scale human trials. You can’t even get them legally from a pharmacy with a prescription to treat a medical condition. Unlike a vaccine there is no motivation to rush this process, so it’s not really legal to sell this stuff in the developed world. Whoever is selling you this right now is by definition kinda shady and bypassing all sorts of safeguards that are usually in place before these things hit the market, and even then it could possibly be prescription only. You have no way of verifying if the product is legitimate because there is no established process to sell them. Any lab producing this is doing so for experimental research, so at best you are getting whatever they inject into animals during trials. At worst, it is just some expensive random stuff. I have no idea how you would find a trusted source like those mentioned in
https://sculptnation.pissedconsumer.com/customer-service.html for something that is not legally sold unless you run your own lab. There is no information on approved doses or medical contraindications. Unless you are dealing with a serious disease and willing to take unknown risks, I do not see why anyone would take it. If someone really was desperate about some joint disease or injury, I’d probably go with platelet rich plasma or something like that, which at least is produced from stuff in your own body and administered by a doctor, instead of an unknown drug.