Your living situation wasn't going to last forever so at some point the band aid had to be ripped off. At this point you've just gotta work on yourself. If you have no roots there, then there are plenty of not so fun but high paying jobs that you could take around the country that might suck but will get you a nest egg quickly so you won't have to worry about rent and bills for a while.
You may be an introvert but your communication on here tells me you shouldn't have a problem making friends. We all need human interaction and your friend and his wife's family aren't your last and only acquaintances in life. Friends, like women, don't just fall in your lap. I've made friends at every job I've been at although I did have one job where I just had nothing in common with anyone and was a bit of an outcast, which I wasn't used to being in any situation. So I can see maybe not liking anyone at a warehouse job but if you're going through multiple jobs and you really don't like anyone enough to be friends with, then maybe you're just too picky or you let things get under your skin that maybe aren't that big a deal in the grand scheme of things?
I dunno man, just throwing stuff out there. I don't like seeing people struggle but at the same time nothing will improve until you point the finger back at yourself and work on you. Ideally you'd want to get to the point where maybe a friend does fuck you over but that's okay because you have a half dozen more anyway.