Supplements Methylene blue

[Romulas]

I'm about 6 weeks in and recently added red light therapy into the mix and still don't feel any difference. Does anyone have any personal experience with it they can share?



I'm an avid health/anti aging advocate. I'm 42, in great shape for any age and have a variety of health regimens in place like a supplement and vitamin schedule, home sauna, bjj black belt training 3x a week, lift weights 2x a week and eat extremely healthy foods. I've also done stem cell therapy, use peptides, gave trt a try a few years back and do a variety of anti aging protocols.

I'm willing to try anything and usually get some measurable results but after taking Methylene blue, I feel nothing.

 

[Deaths Head]

If your in peak conditioning you might not feel it , a common mistake is everyone expecting reverse aging but it’s about maintaining. It might be working you won’t actually know bc it’s not an enhancing as far as working out like creating , Carnosyn etc where you will feel it . From what I read it’s synthetic and needs high dosages to work at its best .

Like most things long time use and consistency is needed , maybe someone not at optimal health might feel it more ? There are ways to bring dead cells back ( anastasis ) but imop creatine which helps mitochondria which makes cells live much longer is definitely needed in anyone’s anti aging crusade .


Not to read the whole article ( it’s long and ……) this is another supplement I’ve been on since around 2002 .

Agmatine Improves Cognitive Dysfunction and Prevents Cell Death in a Streptozotocin-Induced Alzheimer Rat Model - PMC

Alzheimer's disease (AD) results in memory impairment and neuronal cell death in the brain. Previous studies demonstrated that intracerebroventricular administration of streptozotocin (STZ) induces pathological and behavioral alterations similar to ...

pmc.ncbi.nlm.nih.gov

 

[Romulas]

If your in peak conditioning you might not feel it , a common mistake is everyone expecting reverse aging but it’s about maintaining. It might be working you won’t actually know bc it’s not an enhancing as far as working out like creating , Carnosyn etc where you will feel it . From what I read it’s synthetic and needs high dosages to work at its best .

Like most things long time use and consistency is needed , maybe someone not at optimal health might feel it more ? There are ways to bring dead cells back ( anastasis ) but imop creatine which helps mitochondria which makes cells live much longer is definitely needed in anyone’s anti aging crusade .


Not to read the whole article ( it’s long and ……) this is another supplement I’ve been on since around 2002 .

Agmatine Improves Cognitive Dysfunction and Prevents Cell Death in a Streptozotocin-Induced Alzheimer Rat Model - PMC

Alzheimer's disease (AD) results in memory impairment and neuronal cell death in the brain. Previous studies demonstrated that intracerebroventricular administration of streptozotocin (STZ) induces pathological and behavioral alterations similar to ...

pmc.ncbi.nlm.nih.gov

Thanks for the awesome reply! Looked over that study and will get more into it this weekend. I ordered agmatine. Alzeimers runs in my family.

I take creatine daily (only 1 gram unless I'm training for something) same with both of my kids.

Do you take resveratrol?

 

[Deaths Head]

Thanks for the awesome reply! Looked over that study and will get more into it this weekend. I ordered agmatine. Alzeimers runs in my family.

I take creatine daily (only 1 gram unless I'm training for something) same with both of my kids.

Do you take resveratrol?

Yea every week ( red wine ) , I mix a glass or two in my drink sometimes, I used to take resveratrol in a anti aging formula back in the early 2000”s . I find red wine gives me more nitric oxide on top of the other stuff .


I’ve taking creatine since 1992 dosages vary per individual myself I take 5 grams a day or 10 on intense days . Agmatine may not work as fast as other supplements it works best for intense training as well I mix Carnosyn with it ,I always mix creatine and Carnosyn together or Carnosyn and Agmatine ,I keep creatine and Agmatine separately as it might be counter active to each other .

 

[Berserker13]

NAD +

 

[Berserker13]

Yea every week ( red wine ) , I mix a glass or two in my drink sometimes, I used to take resveratrol in a anti aging formula back in the early 2000”s . I find red wine gives me more nitric oxide on top of the other stuff .


I’ve taking creatine since 1992 dosages vary per individual myself I take 5 grams a day or 10 on intense days . Agmatine may not work as fast as other supplements it works best for intense training as well I mix Carnosyn with it ,I always mix creatine and Carnosyn together or Carnosyn and Agmatine ,I keep creatine and Agmatine separately as it might be counter active to each other .

Agmatine is one of the best overall supplements I've taken

 

[Deleted member 609094]

Thanks for the awesome reply! Looked over that study and will get more into it this weekend. I ordered agmatine. Alzeimers runs in my family.

I take creatine daily (only 1 gram unless I'm training for something) same with both of my kids.

Do you take resveratrol?

Creatine in spite of training in doses of at least 5g is starting to be shown as beneficial in health.

I'll look for some links to edit in.

 

[Romulas]

Creatine in spite of training in doses of at least 5g is starting to be shown as beneficial in health.

I'll look for some links to edit in.

I was taking 5 grams a day up until a year ago. I do extensive bloodwork panels and one of the anti-aging doctors (that didn't know I was taking creatine)saw my blood work and mentioned that he's had patients in their 50's that have issues from long term large dose creatine. He only recommended doing 5-7grams on days I'm training.

I've hearing podcasts about higher dosages being fine though. If you find some more material I'd love to check it out! Thank you.

 

[wufabufa]

I was taking 5 grams a day up until a year ago. I do extensive bloodwork panels and one of the anti-aging doctors (that didn't know I was taking creatine)saw my blood work and mentioned that he's had patients in their 50's that have issues from long term large dose creatine. He only recommended doing 5-7grams on days I'm training.

I've hearing podcasts about higher dosages being fine though. If you find some more material I'd love to check it out! Thank you.

Was your doctor only looking at creatinine numbers for your kidney function?? If so, supplementing creatine can make those values go up and looks like you've got kidney failure. Ask for a cystatin-C on your next round of blood work if your creatinine is high. It's a marker of kidney function that isn't impacted by diet, supplementation, hydration, amount of skeletal muscle, or exercise. I've had this issue before and only one Dr I've ever seen knew to make that adjustment when I told her about my creatine supplementation. My cystatin-C came back totally normal.

 

[Romulas]

Was your doctor only looking at creatinine numbers for your kidney function?? If so, supplementing creatine can make those values go up and looks like you've got kidney failure. Ask for a cystatin-C on your next round of blood work if your creatinine is high. It's a marker of kidney function that isn't impacted by diet, supplementation, hydration, amount of skeletal muscle, or exercise. I've had this issue before and only one Dr I've ever seen knew to make that adjustment when I told her about my creatine supplementation. My cystatin-C came back totally normal.

Exactly what you said happened. I wasn't aware of Cystatin-C. That's another test?

 

[Romulas]

Agmatine is one of the best overall supplements I've taken

I've been taking 1 gram a day (reccomend on the bag). I bought a kilo and add it to my morning routine drink.

I'm 6'3" around 200lbs. Is 1 gram sufficient?

 

[wufabufa]

Exactly what you said happened. I wasn't aware of Cystatin-C. That's another test?

Correct. During routine bloodwork you can ask for a cycstain-c as part of it instead of them checking creatinine levels for kidney function. Cystatin-c tends to be a lot more sensitive and accurate. If your Dr doesn't know about it or won't order the test for you, then find one who is better informed.

 

[Berserker13]

I've been taking 1 gram a day (reccomend on the bag). I bought a kilo and add it to my morning routine drink.

I'm 6'3" around 200lbs. Is 1 gram sufficient?

try one in the am and maybe one in the afternoon as a test

 

[Trabaho]

You can´t beat father time.

 

[Ladder Master]

There is about to be a huge change.
Early 40's are not that bad and then BOOM!



"We're not just changing gradually over time; there are some really dramatic changes," said Michael Snyder, PhD, professor of genetics and the study's senior author. "It turns out the mid-40s is a time of dramatic change, as is the early 60s. And that's true no matter what class of molecules you look at."

Massive biomolecular shifts occur in our 40s and 60s, Stanford Medicine researchers find

Time marches on predictably, but biological aging is anything but constant, according to a new Stanford Medicine study.

med.stanford.edu

Why Aging Comes in Dramatic Waves in Our 40s and 60s

A new study suggests that waves of aging-related changes occur at two distinct points in our life

www.scientificamerican.com

 

[BJ@LW&WW]

considering there are zero studies that show benefit of methylene blue use in healthy humans, its not exactly surprising.