Is synthetic Vitamin D worthless?

payton

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In 2009 (endocrinologist/epidemiologist JoAnn Manson M.D.) and her team (at Harvard Medical School) embarked on the world’s largest and most far-reaching randomized vitamin D trial, called VITAL.
The study followed nearly 26,000 generally healthy adults, randomized to receive either 2,000 international units (IU) of vitamin D or a placebo, for an average of 5.3 years.
The results came as a shock….[Vitamin D did not] make a dent in rates of cancer or heart disease….did not prevent falls, improve cognitive function, reduce atrial fibrillation, change body composition, reduce migraine frequency, improve stroke outcomes (etc.).

Scientific American says that extra vitamin D also didn’t lower diabetes risk.
For example, Scientific American says that extra vitamin D also didn’t lower diabetes risk, citing a trial published in 2019 where endocrinologist Anastassios G. Pittas, MD, of Tufts University randomized more than 2,400 people at risk for diabetes to take either 4,000 IU of vitamin D or a placebo daily.
After two and a half years, says the magazine, “a similar number of people in each group went on to develop the disease.”3


 
PRI_220304124.jpg


In 2009 (endocrinologist/epidemiologist JoAnn Manson M.D.) and her team (at Harvard Medical School) embarked on the world’s largest and most far-reaching randomized vitamin D trial, called VITAL.
The study followed nearly 26,000 generally healthy adults, randomized to receive either 2,000 international units (IU) of vitamin D or a placebo, for an average of 5.3 years.
The results came as a shock….[Vitamin D did not] make a dent in rates of cancer or heart disease….did not prevent falls, improve cognitive function, reduce atrial fibrillation, change body composition, reduce migraine frequency, improve stroke outcomes (etc.).

Scientific American says that extra vitamin D also didn’t lower diabetes risk.
For example, Scientific American says that extra vitamin D also didn’t lower diabetes risk, citing a trial published in 2019 where endocrinologist Anastassios G. Pittas, MD, of Tufts University randomized more than 2,400 people at risk for diabetes to take either 4,000 IU of vitamin D or a placebo daily.
After two and a half years, says the magazine, “a similar number of people in each group went on to develop the disease.”3


It's true. Speaking from personal experience Boise dimes much prefer my natural vitamin D injection than their synthetic vibrator Vitamin D
 
If you read the article you linked, the whole thing is a rebuke of the VITAL study and their conclusion that D vitamin supplementation doesn't effect outcomes like CVD and cancer. The authors of the article argue that the RCT had too many biases and their design wasn't suited for testing the hypothesis. These biases included having people with already high baseline D-vitamin values, allowed the placebo group a daily intake of D vitamin and more. They also wont re-analyze their data under more suitable criteria and research money is drying up.

I think it's safe to say that supplementation doesn't work as well as getting your vitamins from the main sources like food and the sun. In regards to the effect of supplementation on the specific outcomes of cancer and the heart, I'd say there is little current evidence to show that it works. That might be because it wasn't done well enough, but the point remains. In regards to diabetes risk, there does seem to be some evidence that supplementation may lower it a small amount. As far as depression and mood, there is some evidence there as well, but again, not set in stone.

Overall, the jury is still out and milage may vary, but as supplements go it's not the worst choice if you have low D-vitamin levels. Although getting fresh air and sunlight, if possible > any supplementation.
 
All supplements for vitamins are generally useless, unless you have a deficiency in that vitamin, then it will be a miracle cure for you. This is why unless you test and specifically know what you're deficient in, a multivitamin is the way to go if you are going to take anything.
 
PRI_220304124.jpg


In 2009 (endocrinologist/epidemiologist JoAnn Manson M.D.) and her team (at Harvard Medical School) embarked on the world’s largest and most far-reaching randomized vitamin D trial, called VITAL.
The study followed nearly 26,000 generally healthy adults, randomized to receive either 2,000 international units (IU) of vitamin D or a placebo, for an average of 5.3 years.
The results came as a shock….[Vitamin D did not] make a dent in rates of cancer or heart disease….did not prevent falls, improve cognitive function, reduce atrial fibrillation, change body composition, reduce migraine frequency, improve stroke outcomes (etc.).

Scientific American says that extra vitamin D also didn’t lower diabetes risk.
For example, Scientific American says that extra vitamin D also didn’t lower diabetes risk, citing a trial published in 2019 where endocrinologist Anastassios G. Pittas, MD, of Tufts University randomized more than 2,400 people at risk for diabetes to take either 4,000 IU of vitamin D or a placebo daily.
After two and a half years, says the magazine, “a similar number of people in each group went on to develop the disease.”3



10,000 IU is the standard dose currently reccomend and you need to take with vit K2 in order to benefit.

You also still need to get sun directly on your skin daily.
 
I was once severely deficient in Vitamin D. Six months later i ended up with a little over double the amount of Vitamin D that a healthy person should have.[most people don't though.]
I started swimming in an outdoor pool 5 days per week, which was about four and a half years ago.
Show as much skin to the sun as you can. Don't believe the lies about having to use sunscreen. And be sensible as to when you get in the sun, and for how long.
 
PRI_220304124.jpg


In 2009 (endocrinologist/epidemiologist JoAnn Manson M.D.) and her team (at Harvard Medical School) embarked on the world’s largest and most far-reaching randomized vitamin D trial, called VITAL.
The study followed nearly 26,000 generally healthy adults, randomized to receive either 2,000 international units (IU) of vitamin D or a placebo, for an average of 5.3 years.
The results came as a shock….[Vitamin D did not] make a dent in rates of cancer or heart disease….did not prevent falls, improve cognitive function, reduce atrial fibrillation, change body composition, reduce migraine frequency, improve stroke outcomes (etc.).

Scientific American says that extra vitamin D also didn’t lower diabetes risk.
For example, Scientific American says that extra vitamin D also didn’t lower diabetes risk, citing a trial published in 2019 where endocrinologist Anastassios G. Pittas, MD, of Tufts University randomized more than 2,400 people at risk for diabetes to take either 4,000 IU of vitamin D or a placebo daily.
After two and a half years, says the magazine, “a similar number of people in each group went on to develop the disease.”3


Not reading all that. I eat salmon and go outside for vitamin requirements.
 
Many people have problems with getting vitamin D through their digestive system. For them oral supplements are ineffective.
Overall vitamin D in adequate amounts brings the quality of life up by a lot.
 
I used to be a big supporter of taking vitamin D3. It appeared to help many once they reach a testing result of 50ng/ml and higher from what i was reading.

Then I began to have doubts the vitamin D pills were being all that helpful. Now I personally do not take a vitamin D capsule but instead make it a point to obtain some sensible sunshine exposure most days. That seems to give me greater health benefits.
 
I'll still take vitamin D pills during the winter when the sun makes a rare appearance
 
Vitamin D helps vitamins and nutrients absorb better. Since I started supplementing with it, my blood work has come back better and better. I don't drink Milk. So I supplement after my doc said my levels were low.

D is my base. Then:
Milk Thistle for liver.
B complex for Blood, BP, Liver, Brain, Digestion.
Magnesium for Sleep and Lower blood sugar.
Fish Oil for lower Triglycerides and raised good cholesterol.

I know they all work because I added them when my blood work showed something needing fixing. When I added the supplement, the next test came back perfect.
 
Cod liver oil might work. It contains vitamin D that the fish itself already processed. Liver is the organ that stockpiles many fat soluble vitamins. Back in the day in Canada people used to force themselves to take a tablespoon every once in a while during the winter.
 
I take it daily.

My current stack:

Vitamin D
B Complex
Fish Oil
Iron
Magnesium
Rhodiloa (3xs a week)
Creatine
Inositol
 
My daily supplement intake is:

Vitamin B, C and D
Calcium
Magnesium
Zinc
Cod Liver Oil
Multivitamin with Iron
Turmeric
 
Correct me if I’m wrong, but vit D drops administered sublingually bypass the digestive system and hit the bloodstream directly, as opposed to just swallowing a pill.

Many people have problems with getting vitamin D through their digestive system. For them oral supplements are ineffective.
Overall vitamin D in adequate amounts brings the quality of life up by a lot.
 
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