Chemical interference
High doses of Salicylate (Aspirin) have been found to interfere with the most commonly used drug screening technology. Salt, vinegar, bleach, Visine, nitrites and chromates are other examples of substances that have been used to beat the test.
Masking
Masking involves the use of a drug or chemical to alter the pH of blood or urine. Armstrong's drug of choice was the blood booster EPO. When injected directly into the vein this anemia drug would be gone without a trace in a matter of hours. Therefore, Armstrong and his teammates would time their usage. In a pinch, a doctor would smuggle Armstrong a saline infusion that would dilute his blood.
What's the Big Idea?
Only time will tell if Lance Armstrong gets a pass from his fans (including this writer, who is still quite dumbstruck), as well as from the law. However, the big idea behind this story is bigger than Lance Armstrong. Athletes like Armstrong are exemplary scenarios, embodying a desire that the rest of us possess, which is to upgrade our biology. That is why athletes are on the leading edge of techniques to defeat the drug monitoring process. Armstrong's case shows us just how effective these efforts can be. Armstrong evaded testers for over a decade, using a wide array of techniques.