I wouldn't say they're an inherently dangerous lift; they do seem to have a clinical function, when done with strict form and with little resistance. That said, I do beleive the way most lifters do them(relatively heavy weights, not controlling for velocity/momentum) is likely a detriment to the overall integrity of the patella. Quite simply, it's a biomechinically disadvantageous position, and places a lot of shearing force on the joint.
Bottom line(for me) is that any benefit is far outweighed by risk with this lift, so I won't do it unless prescribed by a PT, etc. This is particularly the case given that there is virtually zero carryover to sport and/or ADL's, and there are vastly superior ways to train knee extension and increase strength/hypertrophy in the quads. I don't see the point of doing them in a universe that contains squat, lunge, leg press, etc variations. Just my .02.