Prem fred post season rigamortis edition

Biggest World Cup flop?


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Willian covering up Conte with trophies, apparently he doesn't like him.

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There's your drama for the day.
 
Everyone piling on the easy clear choice favorite in poll

buncha fn bullies itd
 
Willian covering up Conte with trophies, apparently he doesn't like him.

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There's your drama for the day.

Conte is a fucking winner

wish we had him
 
Seems a good fit. He's leaving, he lives in London, he's a winner. But no, we go all in on fucking Arteta.

Did you really think the board was gonna go after an established name?
 
lol there's no way im gonna be able to memorise all this shit. Taking the L now.

Shigella which causes dysentery, releases shiga toxin that cleaves adenosine from rRNA preventing the cell from producing proteins. C. diptheriae which causes diphtheria ADP-ribosylates EF-2 so doesn’t work. Because the binding domains of the toxins are different this is why the diseases are different.

Diphtheria:

Diptheria is an upper respiratory tract infection of the pharynx caused by corynebacterium diptheriae that multiplies in a non-invasive manner. However the toxin despite being produced locally acts at a distance, it is absorbed into the lymphatics resulting in systemic effects such as : Fever, pallor, weakness, polyneuritis, myocarditis

This damages the heart, kidney, nerves and adrenals


Toxin kills epithelial cells, can cause ulcers, a pseudomembrane, massive local swelling resulting in a Bull Neck and respiratory obstruction.

All of this is due to the toxin, if a mutant is made that cannot produce the toxin, the corynebacterium diphtheriae has no virulence. Corybacterium diphtheria is a gram +ve non-mobile rod

Travellers Diarrhoea:

Damages intracellular signalling in enterotoxins, the heat-stable E.coli toxin by causing changes in guanylate signalling. The E.coli heat labile toxin by causing changes in adenylate cyclase. Resulting in loss of Cl-, fluids and diarrhoea. Cholera toxin works in a similar way interfereing with processes inside enterocytes resulting in water loss.

Tetanus:

Tetanus used to be called lock-jaw or oposthtonus. Caused by Clostridium tetani that secretes tetanus toxin resulting in a spastic paralysis. The tetanus toxin is a Zn2+ endopeptidase for synaptobrevin.
 
that's literally one page out of like 80 lol
 
my plan of getting top 10% of the year has gone to just pass lol
 
Nah son

Full Time Devils is shit

United Stand with Flex and Soph made me consider becoming a United fan, until I remembered Maureen is your manager

United Stand in the year 2237: We're only 3 more signings from winning the League
 
Seems a good fit. He's leaving, he lives in London, he's a winner. But no, we go all in on fucking Arteta.
why do i sense some desperation in you Connie lad ? Helax, you´ll be fine, Arteta will be outstanding. imo you should be positive and embrace him as your new manager.
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Why wouldn't they? Even Wenger had been a manager for 12 years when he joined us.

Because names usually want power and competitive transfer budgets.

Should go after Eddie Howe, imo.
 
why do i sense some desperation in you Connie lad ? Helax, you´ll be fine, Arteta will be outstanding. imo you should be positive and embrace him as your new manager.
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My disappointment is immeasurable, and my day is ruined.
 
United Stand in the year 2237: We're only 3 more signings from winning the League
Like Tules says, The united stand is the one. The interviewer is way more likable than the guy doing interviews for FTD.
Need to say I only watch the post match rants.
 
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