Economy FDA Approves Neffy, An Effective $25 Nasal Sprays Alternative To $600 EpiPens

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Watch, once this inexpensive nasal spray floods the market, EpiPen's astronomical price tag will magically drop from the sky!

FDA approves nasal spray alternative to EpiPen




The Food and Drug Administration approved a new nasal spray that will be an alternative to EpiPen for people who have severe allergic reactions.

The medication is called Neffy, an epinephrine spray that can help stop the effects of a severe allergic reaction, called anaphylaxis, to food, medications and insect stings, The Washington Post reported.

It is done with a single spray in one nostril. The person does not have to be breathing to have the spray used. It is absorbed by the nasal mucosa, USA Today reported.

Traditionally an auto-injecting device like an EpiPen has been used to stop anaphylaxis, which some people may be hesitant to use because of a fear of needles. That fear can either delay or prevent treatment.

“People don’t want to inject themselves, so they wait and hesitate,” Richard Lowenthal, chief executive of ARS Pharmaceuticals, the company that developed Neffy, said according to the Post.

“The needle-free device removes the fear of needle-based injections and may be easier to use,” Kathy Przywara, community vice president of the Asthma and Allergy Foundation, said, according to USA Today. “This may increase confidence among people managing life-threatening allergies.”

Neffy will come in a two-pack of single-use devices. It will cost $25/copay for people with insurance and after coupons are added. It will be $199 if you pay in cash, The Washington Post reported.

The FDA had asked ARS for more studies on the medication last year. In the end, the approval came for use in adults and children who weigh at least 66 pounds.

The company conducted four studies looking at 175 healthy adults who don’t have anaphylaxis and found that Neffy left a similar amount of epinephrine in the system as injectable treatments.

Neffy should be available in the U.S. in about eight weeks.

 
Previously:

Why Did Mylan Hike EpiPen Prices 400%? Because They Could​


The U.S. stands out as the most expensive market for EpiPens, despite over 1 million Americans having epinephrine prescriptions. After Mylan acquired the rights to produce EpiPens in the U.S. in 2007, the cost of a two-pack skyrocketed to $600, up from about $60.

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Neffy will come in a two-pack of single-use devices. It will cost $25/copay for people with insurance and after coupons are added. It will be $199 if you pay in cash, The Washington Post reported.
Still a ridiculous price for what it is. FDA loves granting and allowing monopolies over products that aren't even "new" or "novel" by any stretch.
 
Still a ridiculous price for what it is. FDA loves granting and allowing monopolies over products that aren't even "new" or "novel" by any stretch.

What in the hell are you complaining about? The fact that there's finally an affordable $25 option, or the fact that there's finally a simple epinephrine nasal spray?
 
What in the hell are you complaining about? The fact that there's finally an affordable $25 option, or the fact that there's finally a simple epinephrine nasal spray?
Some people just live to whine, often about nothing in particular
 
What in the hell are you complaining about? The fact that there's finally an affordable $25 option, or the fact that there's finally a simple epinephrine nasal spray?
Seems pretty obvious what I'm complaining about. Are you illiterate ?
It's a $1 dose of epinephrine and a $4 plastic delivery device they're charging $200 for out of pocket for a drug that isn't new at all.
FDA should be opening the floodgates on any manufacturers that want to produce similar devices...yet they aren't. You dipshits accept a half concession and even cheer for it.
 
Much needed alternative to epi pens. Although there are alternatives. The needle free option is good
 
Still a ridiculous price for what it is. FDA loves granting and allowing monopolies over products that aren't even "new" or "novel" by any stretch.
I don’t see how an item that is not a regularly consumed item being $200 is a ridiculous price. I’m sure if they have it in Europe, where the government is subsidizing it, it’s less money, but that doesn’t make the real cost any cheaper.
 
Still a ridiculous price for what it is. FDA loves granting and allowing monopolies over products that aren't even "new" or "novel" by any stretch.
"For what it is"..... a life saving drug intervention? You're right, just let those genetic defectives perish from their immunological peculiarities. I love how folks just feel entitled to a miracle in a bottle.


Folks should know that there have been alternatives to the Epi-pen, and shit did NOT get any cheaper. Folks should also note that there have been periods of long term shortages for these meds, and being the highest paying consumer meant that the USA has experienced the lowest frequency of same.

That said, I absolutely believe that drug companies are raping the shit out of US citizens, and the Biden administration is the first in history to address this meaningfully and that the Harris administration will absolutely expand this movement.

Lastly, brand name global drug companies have stated for many, many years, that their pricing strategies are for the GLOBAL good. ie) The richer your country is, the higher the prices, and they use that to subsidize provision of drugs to poorer countries. Essentially, as a drug manufacturer, it would be immoral to provide life extending/saving medications ONLY to the rich. So, if you want cheaper drugs, move to a shit hole. In theory I agree with that a lot, but the problem is that there are both affluent and indigent folks in EVERY country, so when it's scaled like that, for equitable access to fulfill that ideal the governments in individual countries have to actually manage their drug supply chain to ensure that all of it's citizens have access, and the US has traditionally had a you're on your own policy for the most part, and who suffers is the average or lower income person on the street. The rich cunts are fine in all countries. Well, most anyway.

Do you think epinephrine grows on trees?
Do you think the research demonstrating the feasibility/reliability/absorption of nasal dosing was free?

Also, it's literally scheduled to be 10x less than the current standard.

Some folks just want to bitch, I guess. It appears I have company in that regard.
 

Biden, Harris hail Medicare drug price cuts that will save billions​

By Jeff Mason, Patrick Wingrove and Trevor Hunnicutt

LARGO, Maryland/WASHINGTON, Aug 15 (Reuters) - The United States has negotiated down the prices of 10 top-selling prescription drugs used by Medicare by as much as 79%, hoping to save $6 billion in the first year as part of a plan hailed on Thursday by President Joe Biden with the aim to ease anger about high prices ahead of November elections.

Biden's signature Inflation Reduction Act, signed into law in 2022, was the first to allow Medicare to negotiate prices for some of the most costly drugs that the program covers for 66 million people. The new prices will go into effect in 2026.

"We finally beat Big Pharma," Biden said at an event in Largo, Maryland, alongside Vice President Kamala Harris.
The administration hopes the savings will ease Americans' anger about high prices, an issue they frequently say is their top concern headed into the closely contested Nov. 5 presidential election between Harris and Republican former President Donald Trump.

"My entire career, I have worked to hold bad actors accountable and lower the cost of prescription drugs," Harris said. "Medicare can use that (collective bargaining) power to go toe-to-toe with Big Pharma and negotiate lower drug prices."

The new prices represent cuts to individual list prices that do not reflect any rebates and discounts the government may already be getting for the drugs, although the government's estimated savings from the negotiations do take those discounts into account.

Harris' tie-breaking Senate vote passed the law that allows for the drug-price negotiations, which no Republicans supported. In a statement, she also pointed to her work as California attorney general holding "big pharma accountable for their deceptive and illegal practices."

Though it was an official event, Biden turned his speech in the gymnasium into a de facto campaign rally, saying Harris would make a "hell of a president" and criticizing Republicans for not supporting Medicare's right to negotiate drug pricing.

Republican House leadership, including Speaker Mike Johnson, described the power as "price fixing" in a statement. "Their prescription drug price fixing scheme has accomplished just two things: driving up health care costs and crushing American innovation in medicine."

The administration said people covered by Medicare, which mostly serves Americans aged 65 and over, would also save $1.5 billion in out-of-pocket costs for the prescription medicines in 2026.

Merck & Co's (MRK.N), opens new tab diabetes drug Januvia faces the steepest percentage price cut of the drugs on the list, decreasing 79%, while Novo Nordisk's (NOVOb.CO), opens new tab insulin aspart products will face the second steepest of 76%, according to the government.

The other eight drugs on the list face cuts of between 68% and 38%.

chart.png

BMO Capital Markets analyst Evan Seigerman said the important comparison for investors would be the difference between the product's newly discounted price and the ultimate net price.

U.S. health secretary Xavier Becerra said in an interview that the government was reluctant to share net prices as they are considered confidential, declining to comment on whether they would be published in the future.

Drugmakers voiced their opposition to the new discounts that they said would not necessarily lower out-of-pocket costs for patients and could hinder future innovation.

Several last month said they did not expect a significant impact on their businesses after seeing the confidential prices from the government.
Vanderbilt University professor Stacie Dusetzina said while the new discounts and savings were encouraging, they were not so aggressive that they would cause concern for the industry.
"It suggests to me that companies are still going to be able to make profits have incentives to innovate," she said.
Shares of Eli Lilly (LLY.N), opens new tab fell by 0.7% while those of Pfizer (PFE.N), opens new tab, Merck and AbbVie (ABBV.N), opens new tab fell marginally in morning trading. Amgen (AMGN.O), opens new tab and Bristol Myers Squibb's (BMY.N), opens new tab shares rose over 1% and U.S.-listed shares of Novo Nordisk were up nearly 2%.

PRICE PAIN​

BMS, which makes the bloodthinner Eliquis, said the 56% price cut to its drug would not solve the "biggest problem in patient affordability" of out-of-pocket costs that are determined by health insurers and pharmacy benefit managers.

Pharmacy benefit managers are companies that handle prescription drug benefits for health insurance companies, large employers, and Medicare prescription drug plans. They negotiate fees and volume-based discounts, known as rebates, on their behalf of payers with drugmakers and pharmacies.

Johnson & Johnson (JNJ.N), opens new tab, whose Crohn's disease medicine Stelara and bloodthinner Xarelto face list price cuts of 66% and 62% respectively, said patients would face higher costs as a result of the price cuts.

Novo and AstraZeneca (AZN.L), opens new tab, whose diabetes drug Farxiga has had its list price cut by 68%, said they were not prepared to leave the Medicare program rather than accept new prices.

A spokesperson for AbbVie, whose cancer drug Imbruvica will face the least steep percentage cut of 38%, said the negotiated price was within the range anticipated.

More than half of voters in 2020 were over the age of 50, and healthcare consumes about 8% of Americans' spending, according to Pew Research Center and Labor Department data.

Inflation has ebbed, but higher prices since the COVID pandemic have left consumers smarting. Consumer prices rose 2.9% over the 12 months through July, and the category including prescription drugs gained roughly the same percentage.

The Medicare agency said it accepted revised counteroffers proposed by the drug manufacturers for four of the 10 selected drugs, while drugs companies accepted its final offers on five.
The administration released its list of the 10 costliest drugs to Medicare that would be subject to negotiations last year.

The pharmaceuticals industry has fought hard to block the Medicare negotiations, with several companies suing the administration and warning that they may have to curtail some drug development programs as a result.

The next round of Medicare drug price talks are expected to include 15 further drugs and begin in February.
Government officials are expected to provide further detail on how they reached the 2026 price cuts next year.

https://www.reuters.com/business/he...-medicare-drug-price-negotiations-2024-08-15/
 
What in the hell are you complaining about? The fact that there's finally an affordable $25 option, or the fact that there's finally a simple epinephrine nasal spray?

He kind of has a point though. It's only $25 co-pay. If you pay cash, it's $200. That means the company is still ripping Medicaid off.
 
- Do you guys pay hight on cialis?
There's should have governament subsides for those medicines.
No govt or work insurance for it. Its like $85 for 4 pills here if I remember correctly. I do not use it too much. Only for sex fuelled (with swinging) vacations in Mexico or Vegas.

@Samjj and Chad TriggeredCuck in case you want to shame me for this too
 
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