Big George was too old and slow. Didn't take much for a skilled boxer to figure him out, especially one as big as Tyson Fury.
If Fury elected to trade with him, it could get interesting. Old George was pretty much immovable and was probably even stronger physically than he was in his prime. Fury's mauling tactics wouldn't work too effectively on him.
If Fury does what he did against Klitschko, though, he's going to pitch a shutout over George. Although I'm not sure if Fury, the fighting man that he is, would be satisfied with doing that. He has got an ego on him, just like Holyfield did, and he wouldn't feel comfortable running away from an old man. There would definitely be some moments where he tries to trade punches with George and feels his power.