International Chinese COVID Vaccines: Brazil's Trial Results Show $75 Sinovac Only 50.4% Effective.

I think for areas that don’t have the infrastructure they’ll have everyone come to a central area to get the shots. Which will make single dose vaccines like JNJ better for these situations. Not too mention no need for crazy freezing

 

https://seekingalpha.com/news/3648167-israel-leads-world-in-covid-vaccinations-per-capita Israel has vaccinated 9% of its population. Helps that they are smaller militarized and have a small population.

Doesn’t help that in the USA millions of doses are sitting on shelf’s due to the USA being Austria Hungary here

 

I think Its the Military behind this and like a lot of Military conspiracies we will most likely not get to know who is behind this unless some hi ranking whistle blowers would surface but I doubt.


And you will not see any much backlash from the government Civilian agencies handling the investigation I am sure the Military will kindly advice them to sweep this under the rugs or they end up inside a cement filed drum.

 

Manila Mayor pledge he will get Moderna and Pfzer it seems there is really distrust and rightfully so with the Chinese vaccines and even Duterte supporters Like Manila Mayor Dumagosu are trying to get independent procurement of vaccines.

They are probably being pushed by the business sector who wants a better vacine that will give more confidence to consumers and investors to get back to normal.


Lots of Filipinos are still worried off getting sick from this and are avoiding going to pubs,theme parks etc, And as long as there are random mini outbreaks it will not put the people at ease.

 

Oh yes this was probably recomended by the Chinese diplomats they have been trying to buy the loyalty of the Philippine military more and more this past few years.

 

Our Mayor wants to wait for the Moderna and Pfzer vaccines instead.

 

I’m sure there is an under current of resistance against some of the crazy things duerte is doing. A more expensive less effective and possibly ore dangerous Chinese vaccine sounds like a dumb plan. Hopefully others can get around dumb D and get the real vaccine

Japan still has no vaccine plan as of now. Maybe this year is all I know

 

Main reason is probably this?

https://en.m.wikipedia.org/wiki/Den...nch,complications associated with the vaccine.


That's a Sanofi issue though.

 

Dengvaxia, there are talks that this whole scandal is just a huge political smere campaign againts the Former president.

But I am not leaning on any side at this point the whole investigation fizled out it seems but I have not read the latest news and articles.

 

Japan is scheduled to begin in Feb, with inventories locked down with Pfizer, Moderna, and AstraZeneca.

 

I mean they are scheduled but don’t have a real plan. I doubt the roll out will be fast by any means. Also seems most don’t want the vaccine. Those that I’ve talked to all are very skeptical

 

China approves Sinopharm Covid-19 vaccine, promises free Chinese shots for all citizens​

China approved its first homegrown coronavirus vaccine for general public use on Thursday, with officials promising to provide the general public with free inoculations.

The approval comes a day after its manufacturer, state-owned pharmaceutical giant Sinopharm, said the vaccine is 79.34% effective, citing interim analysis of Phase 3 clinical trials.

Though no detailed efficacy data for the vaccine has been released, the decision to grant approval underscores claims made by Chinese officials in recent weeks over the safety and effectiveness of the country's domestically produced vaccine candidates.

China is aiming to inoculate 50 million people with domestic Covid-19 vaccines ahead of February's Lunar New Year celebrations. It has also drastically scaled up its vaccine emergency use program in recent weeks.

Zeng Yixin, vice-minister of China's National Health Commission, said at a news conference Thursday that the Sinopharm vaccine will be provided free of charge to Chinese citizens.

"Vaccine is a public good by its nature, and the price may vary based on the scale of use, but an important premise is that it will be provided to the public for free," Zeng said.

Since December 15, more than 3 million vaccine doses have been administered to "key groups," Zeng said. That's on top of the 1.5 million doses administered to "high-risk groups" by the end of November, he added.

Among those inoculated, fewer than 0.1% developed a light fever, and about two people per million developed "relative serious adverse reactions" such as allergies, according to Zeng.

The next step is to inoculate vulnerable groups such as the elderly and people with underlying diseases, before vaccinating the general population, Zeng said, without offering more details on how the vaccines will be provided for free.

A Sinopharm company executive said Thursday the vaccine's Phase 3 trials covered more than 60,000 people, while detailed data will be released later and published in scientific journals at home and abroad.

An official with China's drug regulator said the vaccine's clinical trials are still ongoing, and its manufacturer will be required to submit follow-up data to authorities.

The Sinopharm vaccine is less effective than those developed by Pfizer-BioNTech and Moderna, which have an efficacy rate of about 95%. Russia says its Sputnik V vaccine is 91% effective.

And the vaccine's efficacy rate of 79% is lower than the 86% announced by the United Arab Emirates for the same vaccine on December 9. The UAE based its results on an interim analysis of late-stage clinical trials conducted there from July. It has since approved the vaccine for public use.

The Sinopharm vaccine has a higher efficacy rate than the one developed by the UK's Oxford University and AstraZeneca, which averaged 70%. On Wednesday, the UK became the first country to approve that vaccine for public distribution.

Sinopharm's results were announced weeks after its global competitors. And with a lack of details, it remains unclear whether the information provided will be enough to dispel skepticism over the quality of Chinese vaccines.

Nevertheless, the announcement could still pave the way for the vaccine's large-scale rollout both within China and globally.

China is ready to send hundreds of millions of doses to countries that have conducted last-stage trials for its leading vaccine candidates. Chinese leaders have also promised a growing list of developing countries priority access.

Beijing is using the global campaign as a soft power tool, analysts say, to try to repair any damage to its image from its early mishandling of the coronavirus pandemic.

Aside from the approved Sinopharm vaccine, China has four coronavirus candidates which have reached Phase 3 clinical trials -- the last and most important step of testing before regulatory approval is sought. Having largely eliminated the spread of coronavirus inside its borders, Chinese drugmakers had to look abroad for places to test the efficacy of their vaccines. Together, they have rolled out Phase 3 trials in at least 16 countries.

Sinopharm's two vaccine candidates, including the one approved in China, have rolled out Phase 3 trials in 10 countries, mostly in the Middle East and South America.

Sinopharm chairman Liu Jingzhen said last month that dozens of countries have requested to buy the company's vaccines. He did not name the countries or elaborate on the amount of doses they proposed, but he said CNBG was capable of producing more than a billion doses in 2021.

Compared with Pfizer and Moderna, Sinopharm's vaccines do not require freezing temperatures for storage, making transport and distribution much easier -- especially in developing countries that lack cold storage capacities.

https://www.cnn.com/2020/12/30/asia/china-sinopharm-vaccine-efficacy-intl-hnk/index.html

 

Sounds like they felt that saying 80% or more would be called out as a lie. So they went right below that level

 

Egypt approves Chinese COVID vaccine, roll-out likely this month
Arab world’s most populous country plans to buy 40 million doses of the Sinopharm vaccine, health minister says.

​

https://www.aljazeera.com/news/2021/1/3/egypt-approves-chinese-vaccine-roll-out-expected-in-january

 

SINOVAC VACCINE 78% EFFECTIVE SHOWN IN TRAILS IN BRASIL

This just came out today
https://www1.folha.uol.com.br/equil...8-contra-a-covid-19-em-estudo-no-brasil.shtml

 

Nailed it!

Further details remains to be seen, but this number is much more believable than those fake-ass cherry-picked numbers from a handful of people in Turkey and Indonesia that China wants to consolidate together for a higher average.

As expected, Sinovac and Sinopharm will mainly compete with AstraZeneca in the developing world who missed out or can't afford the premium stuff, though I expect AstraZeneca will win with its much cheaper price tag and peer-reviewed results published in medical journals.

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Butantan announce Sinovac vaccine 78% effective in Brazil trial, experts call for more details
Eduardo Simões​

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https://mobile.reuters.com/article/amp/idUSKBN29C1VZ

 

And it's actually much lower.
https://www.reuters.com/article/us-...-than-60-in-brazil-trial-report-idINKBN29G14W
The best I could find in English but in Portuguese:
https://g1.globo.com/sp/sao-paulo/n...feitos-no-brasil-diz-instituto-butantan.ghtml
My resume:
Anvisa(FDA) criticized Butantan early results, asked for more data and said the actual efficacy is 50.4%.

I think the image is self explanatory due to the similarity of the languages but it grades disease from 0(not infected) to 10(death). 1 being assymptomatic, 2 light symptoms and so on.
It says that in relation to placebo there were no deaths and no hospitalizations, there was a 77.96% reduction in "people that need help"(not sure what it means) and 50.38% reduction in very mild cases.

Anvisa, says though that the data is still incomplete and it cannot allow the vaccine with incomplete data. Bad!


Why it matters and how it matters?
At first glance it's a terrible vaccine, it's expensive, shady data, and it doesn't work that well.
Looking deeper, if the values hold for the population at large it would still be an improvement as people that get the shots will not die.
However, looking even deeper, if 50% or so of the people that get the shot still get sick they still transmit the virus!
If everybody got the injections at once it would make no difference, sure.
As even advanced countries are taking a while to vaccinate their whole populations and half of the people that get the Coronavac vaccine are still infectious and spreading the virus herd immunity will take a whole lot longer to achieve.

The vaccine is low tech, which is great because it can be produced in many countries but it's not cheap. AstraZeneca's vaccine seems to be cheaper and more effective.
My verdict is a big loss for Sao Paulo and China.

 

It was a sham, they announced 78% excluding cases that were of mild symptons. The vaccine is 50% and the local Government made a mockery of the announcement.

Today the actuall institute that made the tests came out with the correct number

Coronavac is a joke

 

WTF, this cherry-picking bs is even worse than AstraZeneca's intial report

If you are fully vaccinated and still get infected, then you are infected. It doesn't matter if the symptoms are mild or severe, you are still a contagious virus factory!

 

Anyone have info on the dosage that is being distributed/given for the Sinovac vaccine? They tested two dosages in their animal trials, but I can’t find any information on which dose is being recommended/given to humans.