International [British COVID Vaccine News] GAVI Says Demand Still Strong For India-made AstraZeneca Vaccine
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Now there's a name that made wave early on and quickly fell behind the pack, much like Novavax. I do know the E.U did put in a preorder of 225M doses with them (pending approval) at €10 (~$12) per shot last November, but in all likelihood they'll probably be playing second-fiddle.
I believe CureVac only have plan to hold their Phase 3 clinical trials in Europe and Latin America, of which the recruitment process barely completed this month, there's literally no trials data for anyone to review, so I find their incredibly optimistic expectation for EMA approval "3-4 weeks from now" to be highly unlikely, given the fact that Novavax published their successful U.K trials result nearly 3 months ago and still isn't approved yet.
Let's circle May 18-27 on the calendar and we'll see how close they are, but I'm predicting that they wouldn't be approved until at least Summer, and by then their overall contribution to the U.K/E.U's 2021 vaccination effort will likely be as minor as J&J in the U.S, especially now that the E.U has decided to bet the entire farm on Pfizer-BioNTech, this year AND the next.
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Now there's a name that made wave early on and quickly fell behind the pack, much like Novavax. I do know the E.U did put in a preorder of 225M doses with them (pending approval) at €10 (~$12) per shot last November, but in all likelihood they'll probably be playing second-fiddle.
I believe CureVac only have plan to hold their Phase 3 clinical trials in Europe and Latin America, of which the recruitment process barely completely this month, there's literally no trials data for anyone to review, so I find their incredibly optimistic expectation for EMA approval "3-4 weeks from now" to be highly unlikely, given the fact that Novavax published their successful U.K trials result nearly 3 months ago and still isn't approved yet.
Let's circle May 18-27 on the calendar and we'll see how close they are, but I'm predicting that they wouldn't be approved until at least Summer, and by then their overall contribution to the U.K/E.U's 2021 vaccination effort will likely be as minor as J&J in the U.S, especially now that the E.U has decided to bet the entire farm on Pfizer-BioNTech, this year AND the next.
Yeah, I think the US and EU markets are almost saturated for now. Even so (source: German finance magazine Capital),
But even without emergency approval, things could move quickly now. In May or June, data are expected to show whether Curevac is safe and effective. That's when formal approval is expected to be filed. Curevac is aiming to produce 300 million doses this year, rising to about a billion by 2022. The company has already produced vaccine, "at risk," according to company spokesman Schüller. These could be delivered immediately after approval.
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As I understand it the EU are paying AZ something like £3 per jab and the UK are paying £14 per jab.
The EU signed their deal 1 day before the UK but AZ (understandably from a certain point of view) decided to ship the more profitable order first.
I think there is no way AZ will not feel the fallout from this. Optics are very important to politicians and quite a few continental leaders got burned by AZ decision.
I predict the fall out for AZ will be much longer than Covid.
The EU signed their deal 1 day before the UK but AZ (understandably from a certain point of view) decided to ship the more profitable order first.
I think there is no way AZ will not feel the fallout from this. Optics are very important to politicians and quite a few continental leaders got burned by AZ decision.
I predict the fall out for AZ will be much longer than Covid.
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The European Commission didn't do much by way of due diligence on the AZ contract and besides I'm not sure how suing is going to speed up supply which is the stated aim of this , and it does seems a little perverse to be suing over supply shortfall when some member states seem reluctant to use the AZ vaccines that are already available within the EU .
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I don't disagree. I think this is all about punishment now. The EU are buying their doses from Pfizer/Moderna and going to sue/regulate the shit out of AZ.
I think the optics of the UK getting a head start in vaccinations (even though they might not finish first) during the wrangling over Brexit has made it bitter. IIRC some Italian or Belgian politician released the pricing difference as a snark against the Brits first only to see it blow up in their face when AZ gave the Brits preferential treatment.
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This opinion might be based on the faulty assumption of pricings. £15/shot is the price the U.K paid for Pfizer, not AZ.
The prices that the U.K and E.U are paying for AstraZeneca are almost the same at around $3-$4 a shot. Yes, there is a slight difference since the E.U's purchase order is larger, but certainly not five times cheaper, and no countries on Earth are paying AZ the same price as Pfizer.
What Covid vaccines cost - and the countries paying over the odds
https://www.theweek.co.uk/951750/what-do-covid-vaccines-cost-who-pays-what?amp
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According to doctors, the death of a young woman was related to AstraZeneca vaccination.
Very tragic, RIP
https://www.welt.de/politik/deutsch...au-hing-mit-AstraZeneca-Impfung-zusammen.html
Very tragic, RIP
https://www.welt.de/politik/deutsch...au-hing-mit-AstraZeneca-Impfung-zusammen.html
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Spain extends AstraZeneca dose gap to 16 weeks, beyond EU approved limit
Reuters | April 30, 2021
Reuters | April 30, 2021
https://www.reuters.com/world/europe/spain-extend-gap-between-astrazeneca-doses-16-weeks-2021-04-30/
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U.K’s Covid vaccine programme on track despite AstraZeneca problems
Three-quarters of population could be fully immunised by first week in August, according to forecasts
Apr 11, 2021
The UK’s vaccination programme is expected to be effectively completed shortly after the US’s this summer, and several weeks ahead of the EU’s effort, despite falling up to six weeks behind because of problems affecting the Oxford/AstraZeneca jab.
Airfinity, which tracks vaccination programmes worldwide, forecasts that 75% of the population can be fully immunised in the UK by the first week in August, a level where herd immunity arguably begins to take effect – though variants and the potential need for booster jabs could impact this significantly.
That would be about a week and a half behind the US, which can reach the same level by late July, but six weeks ahead of the EU, which the company estimates will achieve the same milestone towards the end of September.
“We expect the US to storm ahead. Production is going very well there and they are not exporting any doses,” said Matt Linley, a senior analyst with Airfinity. “The EU is also finally beginning to speed up too. But despite all the recent problems, the UK should still come out very well placed.”
Experts have repeatedly underlined the need for vaccine distribution to be global, including in developing countries, but there has been inevitable focus on frontrunners in the race so far. On Friday, Thierry Breton, the European commissioner leading Brussels’ vaccine taskforce, claimed that “like the fable of the tortoise and the hare”, the initially slow-moving EU vaccine campaign was accelerating as the UK rollout was beginning to flag.
The UK was the first country in the world to start vaccinating with the Pfizer/BioNTech jab last December, and with a seemingly healthy supply of AstraZeneca doses and an extraordinary mobilisation by the NHS, appeared well ahead of the EU, which failed to build up supply and distribution capacity quickly.
In the UK 31.8 million people, or at least 47.6% of the population, have had a first vaccine dose. But Britain’s decision to offer 10 million under-30s a jab other than AstraZeneca because of concerns about links to rare blood clots could delay the programme by up to four weeks, although Airfinity said the impact would depend on when new vaccines were approved and became available. Another fortnight was lost when India held back 5m doses of the same vaccine, the company estimates.
The Novavax jab, which is being produced and bottled in the UK, is expected to be approved in weeks and supplies are being prepared in advance. But in the past week, ministers said that the single-shot Johnson & Johnson jab, which will rapidly speed up any immunisation programme, would not be available until July, though it will reportedly be approved by the UK regulator within days. It is expected to be available in the EU, where it has already been approved, from 19 April.
An average of just over 3m doses a day are being administered in the US with the country benefiting from significant local supply of the Pfizer, Moderna and Johnson & Johnson vaccines. The AstraZeneca vaccine, which it has yet to authorise, may not be needed there.
Meanwhile, across the EU, intense efforts are being made to boost production and distribution as the 27-country bloc reels from a sluggish start worsened by production problems at AstraZeneca’s European plants.
In the past week, the EU ensured that almost all doses made for the company in the Netherlands would stay in the bloc, despite the UK having staked its claim to them. Britain had pressed unsuccessfully for a 50/50 split.
In Germany, GPs – who at the heart of the UK’s distribution success – were finally allowed to administer jabs this week, and in April daily doses per 100 people crept ahead of Britain for the first time since any vaccine became available, according to figures tracked by Our World in Data.
France, which began a lockdown amid rising cases at the end of March, has also closed the vaccination gap with the UK, although it is yet to forge ahead. This week, a plant in Normandy for bottling the Pfizer vaccine opened, and the country plans to have seven jab production facilities operating by the end of the year.
Martin McKee, a professor of European public health at the London School of Hygiene and Tropical Medicine, said: “The UK has benefited because it started earlier, and we are beginning to see other countries catching up. We also had an exceptional effort in the NHS, but you also have [the question of] how long is that sustainable for.”
https://amp.theguardian.com/society...ogramme-on-track-despite-astrazeneca-problems
California celebrates the 50% immunization milestone by reopening Disneyland at 25% capacity. Meanwhile, in Liverpool
Thousands hit Liverpool rave in trial reopening from
lockdown
April 30, 2021
lockdown
April 30, 2021
Thousands of young people partied at a nightclub in Liverpool on Friday, part of a government-backed trial to restart mass audience events as the COVID-19 pandemic recedes further in England.
Around 3,000 revellers aged 18 to 20 danced to pounding music in a warehouse on the docks, in close contact with each other and without wearing masks, according to a Reuters witness.
Attendees at the evening event had to test negative for COVID-19 within 24 hours of the event.
"We're excited. We're all on the verge of tears ready to go in," a student called Josh told the BBC while queuing outside the venue.
The two-day event is part of a pilot scheme to see how more venues can be reopened safely. It also included a soccer cup final attended by 8,000 people on Sunday at London’s Wembley stadium.
Researchers will accumulate data from these events to see how approaches to social distancing and ventilation affect the spread of the virus.
Non-essential retailers in England reopened on April 12 along with pubs and restaurants operating outdoors, and from May 17 restrictions will be lifted further to include indoor hospitality, performances and sporting events.
Prime Minister Boris Johnson hopes to lift the lockdown entirely in June.
https://www.reuters.com/world/uk/thousands-hit-liverpool-rave-trial-reopening-lockdown-2021-04-30/
Gibraltar is pretty much back to normal:
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https://www.medrxiv.org/content/10.1101/2021.04.30.21256383v1
Pre-print (not peer reviewed yet) finds increased SVT risk for older (60+) women, too.
Pre-print (not peer reviewed yet) finds increased SVT risk for older (60+) women, too.
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@The_Renaissance You partying hard over there to celebrate the U.K's 35 Million inoculations milestone brah?
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@The_Renaissance You partying hard over there to celebrate the U.K's 35 Million inoculations milestone brah?
Haha, sadly I don't live near liverpool but my mate from there went and says it was great!
I've been doing a fair bit of socialising with mates in bars the past couple weeks though, outdoors only but the weathers been good for the most part!
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Likewise, it's nice to knock down a few pints and enjoy some hot wings with friends again now that we've successfully beating the pandemic back and things in California are coming back to normal again!
With over 61% of our population already got at least 1 dose, hopefully we will reach herd immunity this summer and set an example for everyone else in the country.
I wish the anti-vaxers in the forum can just realize the simple fact that the quicker we are immunized against the pandemic, the less Covid hospitalization there will be and then there would be no needs for lockdowns like France/Italy/Japan/India/Brazil, where a tiny portion of the population are inoculated and the hospitals are still full of Covid patients.
The WR is well-known for lacking basic common sense, but the fact that the "just the flu" bros who subscribes to the full anti-mask, anti-vax, and anti-lockdown combo are also fighting tooth and nails to help prolonging the pandemic in their country has got to be the dumbest self-defeating shit I have seen this year. Don't they realize they are their own worst enemies?
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Diplomatic immunity
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@The_Renaissance You partying hard over there to celebrate the U.K's 35 Million inoculations milestone brah?
I doubt most of the people in these raves and clubs have had a jab anyway. They're not old enough to have had the jab yet.
What's the average age of a clubber, 25?
