Well the best option to beat Tyron Woolley would most likely be another third fight with Stephen Thompson again lol. But maybe mai if he can takedown woodley. Mai's wrestling has improved but I don't think it's that good enough to beat Tyron Woodley's. The only other real threat assides wonderboy is Rory macDonald and kelvin gastelum. But gastelum now fighting at middleweight and Rory fighting in bellator, neither are going to fight Tyron anytime soon. I don't like mai fighting Tyron I think it is a really bad match up for him du to Tyron's wrestling. Regardless though IMO mai if he beats masdival should fight Tyron next. I could perhaps see masdival ginving Tyron some troubles particularly with his boxing, pressure, and volume of his punches and has decent takedown defence of his own. However Tyron will imo be too much for masdival with both his ability to cover distance, power, and his offensive wrestling will play a big factor. However masdival may have a better chance than mia simply becausehe does not solely rely on his ability to get an instant takedown. He can actaully stand in trade with woodley.
As for heavyweight, an healthy Cain will beat any heavyweight. However I am concerned that heavyweight may no longer exist. Perhaps in the near future Francis Ngou may have a chance to beat stipe with more fights and time that is. Junior dos santos may actually also have the best chance to defeat stipe again in a rematch. However it depends on how Jds chin holds up to this point. I think stipe has improved since the first jds fight. He mixes his takedowns much better now and seems to even further improve his boxing and puts more power/plants more into his shots. I beleive he will be the more durable and complete fighter on the rematch. If he makes it a dog fight with junior he's the aggressor and mixes his wrestling with his boxing he should win. Even if he is not taking him down he is still making junior second guessing and allowing more strikes to be thrown while standing. However Junior has a real good chance at winning too, especailly with his takedown defence and footwork. Footwork will be key for junior to stick and move.