- Joined
- Aug 3, 2008
- Messages
- 15,654
- Reaction score
- 2,471
http://www.medscape.com/viewarticle/884611
Long-term use of high doses of vitamin B6 and B12 supplements has been associated with an increased risk for lung cancer. Overall, men who took these high doses over 10 years had a 2- to 4-fold increased risk for lung cancer compared with men who did not take such supplements, and the risk was particularly elevated among smokers. However, no such increase was seen in women.
These findings come from the Vitamins and Lifestyle (VITAL) cohort study and were published online August 22 in the Journal of Clinical Oncology.
"Our data shows that taking high doses of B6 and B12 over a very long period of time could contribute to lung cancer incidence rates in male smokers. This is certainly a concern worthy of further evaluation," commented lead author, Theodore Brasky, PhD, from The Ohio State University Comprehensive Cancer Center, Columbus, in a statement.
He emphasized, however, that the doses involved were well above those found in a daily multivitamin tablet.