Well I only assumed your stance to TRT in my first post but that kind of clears it up. Sadly I was right on all accounts.
People with primary hypogonadism and other serious illnesses should get on TRT no questions about but its NOT as easy as you make it. Show me the qualified longterm studies on HPTA recovery. They dont exist. The point is. If you are able to restart your HPTA after taking TRT you NEVER needed it to begin with.
Like I wrote its a fad for most just like you. Only 2-3% of all men with these symptoms qualify for TRT based on illness. The huge danger no one talks about is that people dont get further diagnostics / treatment for which very well might be other threatening illnesses be that physical or especially mental.
There is no klimakterium for men. Thats a lie and the problems you also encountered have much much more to do with other illnesses but mostly lifestyle choices including mental health that have a price at that age.
Right now the medical research situation shows some conclusions but you wont like them.
Its inconclusive about the benefits and only studies financed by TRT companies were determined about it.
Testosterone drugs do not extend life,
they slightly improve sexuality,
they do not improve physical fitness,
they do not improve health in old age, mental health problems, or memory.
TRT is no anti aging drug.
Risks are high blood pressure, blood lipids, thrombosis, prostata malfunction, elevated risk for certain cancer. Experts are divided about elevated risk of blood vessel and heart damage. It is assumed it elevates apoplex risk.
We had a huge study in europe with 3300 men 40years old upwards and supposed "TRT" symptoms. The symptoms were not based on low testosterone with only a very small fraction qualifying for TRT.
This is not a summary by myself but the whole doctors association of Germany after extensive research for years and dated 06/2021
sources:
- Ayele HT, Brunetti VC, Renoux C, et al. Testosterone replacement therapy and the risk of venous thromboembolism: A systematic review and meta-analysis of randomized controlled trials. Thrombosis research 2021; 199:123–31. DOI: 10.1016/j.thromres.2020.12.029. www.ncbi.nlm.nih.gov/pubmed/33486321.
- Corona G, Rastrelli G, Di Pasquale G, et al. Testosterone and Cardiovascular Risk: Meta-Analysis of Interventional Studies. J Sex Med 2018; 15(6):820–38. DOI: 10.1016/j.jsxm.2018.04.641. www.ncbi.nlm.nih.gov/pubmed/29803351.
- Diem SJ, Greer NL, MacDonald R, et al. Efficacy and Safety of Testosterone Treatment in Men: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians. Ann Intern Med 2020; 172(2):105–18. DOI: 10.7326/M19-0830. www.ncbi.nlm.nih.gov/pubmed/31905375.
- Junjie W, Dongsheng H, Lei S, et al. Testosterone Replacement Therapy Has Limited Effect on Increasing Bone Mass Density in Older Men: A Meta-analysis. Curr Pharm Des 2019; 25(1):73–84. DOI: 10.2174/1381612825666190206223244. www.ncbi.nlm.nih.gov/pubmed/30727867.
- Loo SY, Chen BY, Yu OH, et al. Testosterone replacement therapy and the risk of stroke in men: A systematic review. Maturitas 2017; 106:31–7. DOI: 10.1016/j.maturitas.2017.08.013. www.ncbi.nlm.nih.gov/pubmed/29150164.
- Tan S, Sohrabi HR, Weinborn M, et al. Effects of Testosterone Supplementation on Separate Cognitive Domains in Cognitively Healthy Older Men: A Meta-analysis of Current Randomized Clinical Trials. The American journal of geriatric psychiatry official journal of the American Association for Geriatric Psychiatry 2019; 27(11):1232–46. DOI: 10.1016/j.jagp.2019.05.008. www.ncbi.nlm.nih.gov/pubmed/31296441.
- Vartolomei MD, Kimura S, Vartolomei L, et al. Systematic Review of the Impact of Testosterone Replacement Therapy on Depression in Patients with Late-onset Testosterone Deficiency. European urology focus 2020; 6(1):170–7. DOI: 10.1016/j.euf.2018.07.006. www.ncbi.nlm.nih.gov/pubmed/30017901.
- Zhang Z, Kang D, Li H. The effects of testosterone on bone health in males with testosterone deficiency: A systematic review and meta-analysis. BMC Endocr Disord 2020; 20(1):33. DOI: 10.1186/s12902-020-0509-6. www.ncbi.nlm.nih.gov/pubmed/32145741.
- Zhang Z, Kang D, Li H. Testosterone and Cognitive Impairment or Dementia in Middle-Aged or Aging Males: Causation and Intervention, a Systematic Review and Meta-Analysis. J. Geriatr. Psychiatry Neurol. 2020:891988720933351. DOI: 10.1177/0891988720933351. www.ncbi.nlm.nih.gov/pubmed/32602403.
- Ayele HT, Brunetti VC, Renoux C, et al. Testosterone replacement therapy and the risk of venous thromboembolism: A systematic review and meta-analysis of randomized controlled trials. Thrombosis research 2021; 199:123–31. DOI: 10.1016/j.thromres.2020.12.029. www.ncbi.nlm.nih.gov/pubmed/33486321.
- Corona G, Rastrelli G, Di Pasquale G, et al. Testosterone and Cardiovascular Risk: Meta-Analysis of Interventional Studies. J Sex Med 2018; 15(6):820–38. DOI: 10.1016/j.jsxm.2018.04.641. www.ncbi.nlm.nih.gov/pubmed/29803351.
- Diem SJ, Greer NL, MacDonald R, et al. Efficacy and Safety of Testosterone Treatment in Men: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians. Ann Intern Med 2020; 172(2):105–18. DOI: 10.7326/M19-0830. www.ncbi.nlm.nih.gov/pubmed/31905375.
- Junjie W, Dongsheng H, Lei S, et al. Testosterone Replacement Therapy Has Limited Effect on Increasing Bone Mass Density in Older Men: A Meta-analysis. Curr Pharm Des 2019; 25(1):73–84. DOI: 10.2174/1381612825666190206223244. www.ncbi.nlm.nih.gov/pubmed/30727867.
- Loo SY, Chen BY, Yu OH, et al. Testosterone replacement therapy and the risk of stroke in men: A systematic review. Maturitas 2017; 106:31–7. DOI: 10.1016/j.maturitas.2017.08.013. www.ncbi.nlm.nih.gov/pubmed/29150164.
- Tan S, Sohrabi HR, Weinborn M, et al. Effects of Testosterone Supplementation on Separate Cognitive Domains in Cognitively Healthy Older Men: A Meta-analysis of Current Randomized Clinical Trials. The American journal of geriatric psychiatry official journal of the American Association for Geriatric Psychiatry 2019; 27(11):1232–46. DOI: 10.1016/j.jagp.2019.05.008. www.ncbi.nlm.nih.gov/pubmed/31296441.
- Vartolomei MD, Kimura S, Vartolomei L, et al. Systematic Review of the Impact of Testosterone Replacement Therapy on Depression in Patients with Late-onset Testosterone Deficiency. European urology focus 2020; 6(1):170–7. DOI: 10.1016/j.euf.2018.07.006. www.ncbi.nlm.nih.gov/pubmed/30017901.
- Zhang Z, Kang D, Li H. The effects of testosterone on bone health in males with testosterone deficiency: A systematic review and meta-analysis. BMC Endocr Disord 2020; 20(1):33. DOI: 10.1186/s12902-020-0509-6. www.ncbi.nlm.nih.gov/pubmed/32145741.
- Zhang Z, Kang D, Li H. Testosterone and Cognitive Impairment or Dementia in Middle-Aged or Aging Males: Causation and Intervention, a Systematic Review and Meta-Analysis. J. Geriatr. Psychiatry Neurol. 2020:891988720933351. DOI: 10.1177/0891988720933351. www.ncbi.nlm.nih.gov/pubmed/32602403.