It's amazing TSR lasted as long as it did, considering how many powerful government agencies it pissed off.
Of course, all the alphabet agencies included (FBI, CIA, DEA, etc.), but the Treasury as well. Bitcoin is outside the purview of the Fed Reserve. Since TSR was probably a huge part of the bitcoin market, taking it down (and potentially seizing all those coins) is going to do huge damage to bitcoins - at least in the short term.
Conspiracies abound that the story of DPR's takedown isn't legitimate, but a parallel construction. That is, the NSA had the intel, then told the authorities where to look so they could build a case. It's possible, but if so, then Tor isn't secure (and some people believe some Tor servers are operated by the government, anyway).
Lots of repercussions here.