There have been many sibling tandems and families as a whole to compete together in MMA, and the categories are listed below. Please read through the categories before submitting an addition.
Brother Teams in the UFC
1) Matt and Mark Hughes, behind the barn
2) Nate and Nick Diaz
3) Rogerio (little) and Rodrigo (big) Nogueira
4) Frank and Ken Shamrock (adopted but fine)
5) Anthony and Sergio Pettis
6) Jim and Dan Miller
7) Joe and Dan Lauzon
8) Matt and Nick Serra
9) Clay and Jason Guida (Jason was on TUF 8)
10) Jake and Jared Rosholt
11) Erick and Augusto Montano
12) Junior and Raphael Assuncao
13) Iuri/Yuri and Ildemar Alcantara
14) Junie and Rob Browning (Rob was on TUF 9)
15) Rashad and Lance Evans (Lance was on TUF 8)
16) Jake and Joe Ellenberger
17) Chris and Brian Camozzi
18) Yuri and Danillo Villefort
19) Cole and Micah Miller (Micah was on TUF 14)
20) Hector and Elias Urbina (Elias was on TUF 23 and CS 8), with Gilbert out there too
21) David and Daniel Teymur
22) Dominick and Alex Reyes
23) Ashkan and Suman Mokhtarian (Suman is on TUF 27)
24) Erick and Gabriel Silva
25) Abu and Ottman Azaitar
Sister Teams in the UFC
1) Valentina and Antonina Shevchenko
Brother/Sister in the UFC
1) Naoki Inoue and MIzuki Inoue
Brothers by Marriage
Tai Tuivasa and Tyson Pedro
Chris Weidman and Stephen Thompson
Brother teams in MMA but not the UFC
Yasuhiro and Toshimichi Akagi
Adlan (UFC), Musa and Beslan Amagov
Karl (Bellator) and Bertrand Amoussou
Kai and Mikuru Asakura (Both Rizin)
Ali (UFC) and Artur Bagautinov
Chase (WEC, Bellator) and Carson Beebe (WSOF)
Gilbert (UFC) and Herbert Burns (One)
Alex (UFC) and Jose Caceres
Myron and Demoreo Dennis
Cody (UFC) and Tyler East
Leon (UFC) and Fabian Edwards (Bellator)
Fedor (Pride, SF, Bellator) and Aleksander Emelianenko
Yasubey (FNG, ACB, KSW) and Felipe Enomoto (One)
Josh (UFC) and BJ Ferguson (Bellator)
Caros (UFC) and Ben Fodor (Phoenix Jones) are adopted brothers
Matt and Mal Foki (Both Pride)
Patricky and Patricio Friere (Both Bellator)
Denis (PFL) and Sergei Goltsov
Hayder (UFC) and Mehdi Hassan
Pat (UFC) and Ryan Healy (Bellator)
Jeremy Horn and Matt Anderson are half-brothers
Enson (Pride) and Egan Inoue
Denis (UFC) and Tommy Kang
Erik (UFC) and Keoni Koch
Naoyuki (UFC) and Hiroki Kotani (Shooto)
Taylor (UFC) and Damien Lapilus
Ilir (UFC) and Arben Latifi
Muhammed (Bellator/SF) and Abdullah Lawal
Thanh (CS) and Vinh Le
Andrew (One) and Andrew Leone (Bellator, ACB)
Kevin (UFC) and Keith Lee
Chuck (UFC) and Sean Liddell
Douglas (Bellator) and Dhiego Lima (UFC)
Abner (UFC) and Jordi Lloveras
Lyoto (UFC/Bellator) and Chinzo Machida (Bellator)
Ian (UFC) and Brad McCall
Michael (UFC) and Brad McDonald
Yaotzin (UFC) and Victor Meza (Bellator)
Bojan (UFC) and Damir Mihajlovic
Vitaly (Bellator) and Dmitry Minakov
Gegard (UFC/Bellator/SF) and Gewik Mousasi
Takaharu and Takehiro Murahama
Viktor (PFL) and Vadim Nemkov (Bellator)
Anthony (UFC) and Chidi Njokuani (Bellator)
Alexandre Franca and Leonardo Nogueira
Alistair (UFC) and Valentijn Overeem (Pride)
Rousimar (UFC) and Rick Palhares
BJ (UFC) and Reagan Penn
Mariusz (KSW) and Krystian Pudzianowski
Khalil Rountree (UFC) and Donavon Frelow (DWTNCS) are step-brothers
Mauricio (UFC/Pride) and Murilo Rua (Pride)
Daniel (UFC) and Guilherme Sarafian
Justin (UFC) and Jared Scoggins
Edmen (UFC) and Leon (CS) Shahbazyan
Chris and Andreas Spang (Bellator)
Cub (UFC) and Steve Swanson
Bentley (UFC) and Kevin Syler
Anatoly and Vladimir Tokov (Bellator)
Kamaru (UFC) and Mohammed Usman
Vagab and Islam Vagabov
Marcus and Johan Vanttinen
Adam (UFC) and Abukar Yandiev
David (UFC) and Martin (KSW) Zawada
Cousins in the UFC:
Khabib, Umar and Abubakar Nurmagomedov (Abubakar is cousin and adopted brother)
Cousins in MMA:
Alexey Oleynik (UFC) and Alexander Butenko
Royce, Renzo and Roger Gracie (they have a separate category below)
Pat and Jeff Curran
Brother/Sister teams in MMA but not the UFC:
Freddy and Veta Arteaga (Bellator)
Cindy (UFC) and Ben Dandois
Rodrigo (UFC) and Carina Damm (All the Mans)
Cris (UFC) and Rafael Justino
Angela (ONE) and Christian Lee (ONE)
Gina (UFC) and Dave Mazany
Sage (UFC) and Colbey Northcutt (LFA)
Sisters in MMA:
Jocelyn Jones-Lybarger (UFC) and Jillian Lybarger
Family teams in MMA:
Ray Cooper Jr. and Ray Cooper III (PFL)
Randy (UFC) and Ryan Couture (UFC/Bellator)
Kevin [Kimbo] (UFC) and Kevin Jr. Ferguson (Bellator)
Antonio (UFC) and A.J. McKee (Bellator)
Jordan (UFC) and Lee Mein
Father Telman Piraev, and sons Marif and Akhmed Piraev
Ken (UFC) and Ryan Shamrock
Brother Norifumi "Kid" (UFC), Sister Miyuu and son Arsen Yamamoto (Both Rizin)
The Gracie Family:
Rickson "By Armbar" Gracie
Royce Gracie
Renzo Gracie
Royler Gracie
Ralph Gracie
Ryan Gracie
Rodrigo Gracie
Daniel Gracie (Simoes)
Robin Gracie
Roger Gracie
Cesar Gracie
Ralek Gracie
Igor Gracie
Rolles Gracie
Neiman Gracie (Stambowsky)
Kron Gracie
Kyra Gracie (Guimaraes)
Khonry Gracie
And many more...
BROTHERS WHO HAVE FOUGHT EACH OTHER
Jeremiah Castillo vs. Angel Castillo
Caros Fodor vs Ben Fodor
Shunichi Shimizu vs Toshihiro Shimizu
Thomas Treadwell vs. Mike Treadwell