Let’s sum of the results of this study and others:
• One group used oral arginine in this study, but oral arginine supplementation doesn't affect blood flow.
• The arginine group used "time release" arginine, but so-called time release arginine is not actually time released.
• The trained individuals in the NO2 group got stronger without increasing muscle growth, but trained individuals get stronger mostly due to muscle growth.
• The training program and diet alone yielded a six pound increase in bench 1RM, yet four grams of NO2 taken three times a day tripled strength gains on the same program.
In short, something just isn't right.
But Wait, I Thought I Felt Something!
I’m sure some people are reading this and thinking, "But I know these products work because I’ve taken them and feel their effects!" While these perceived effects are potent, I submit to you that based on the scientific evidence, this is merely a result of the placebo effect.
The placebo effect is when someone uses an inert substance, which should produce no effect, yet somehow still experiences an effect. This occurs frequently when pharmaceutical companies test a new drug. They give one group the real drug and another group an inert sugar pill. Interestingly, the group receiving the sugar pill often has a series of side effects like dry mouth, headaches, dizziness, adding ten pounds to their bench, etc. — all caused by their own minds!
One famous research analysis calculated the placebo effect to account for 75% of a drug’s effect, although this exact figure remains controversial (19). It’s amazing what dogma we can succumb to in the face of contrary reason and evidence, merely because we want to believe something. This belief, desire and trust all seem to work at the neurological level of the brain (10). This indicates that it’s more than a matter of a few people being tricked by unscrupulous companies.
Unfortunately, the situation is even worse when it comes to sports supplements because of our expectations. Hundreds of advertisements with spectacular claims, combined with our incredibly strong desire to believe that these supplements work, often defeat our poor psyches. I call this a directed placebo effect, because we have not only a simple belief in what the supplement is supposed to do, but a powerful desire to believe in its effectiveness.
What can make our desire to believe in these products even stronger is the very fact that we've already purchased them! After all, recognizing that a product doesn’t work is like admitting that we were duped — something no one wants to do. Hey, I've fallen into this trap too in the past. We're all susceptible.