Yes, probably. Classic Strange was a bit like Silver Age Superman or Adam West’s Batman – the writers back then used plot devices like it was going out of style. Classic Strange always had some magical trick of, when you thought about it, *immense* power he could pull out at the 11th hour and banish the bad guy back to Agamemnon’s butt crack.
Comics were different back then. I’m reading through classic Thor right now and Thor, who through the 90’s and 2000’s routinely got trounced by Thanos, was pulling tricks out in the 60’s which were *far* above his power scale for the decades that followed – and then he’d never use them again even when it would be an easy solution to his weekly life-threatening challenge. Comics were just different back then, and classic Strange probably would have had an anti-Titan spell handy for a fight with Thanos. It’s almost apples to oranges, with comics in the late 70’s, 80’s and 90’s becoming a bit more grounded before they started going all DBZ in the 2000’s, but I strongly suspect classic Strange would take out Thanos. Hell, even current Strange would pose an interesting challenge for Thanos, though I think Thanos would take it. That being said, I’ve heard that Strange with all of his artifacts is Skyfather level, with Thanos being a low-Skyfather level, so..
If you’re interested, here are the
real geeks on the subject…
http://comicvine.gamespot.com/forums/battles-7/dr-strange-vs-thanos-402989/
Post #39 is particularly informative.