Best acting of all time from a main character in a TV show?

I've only just got into Frasier .
And watched nearly all of it on last series
Great actor liked john Mahoney too
yeah he played that character for over 20 years... two shows and played it on an episode of wings too.
 
I'm going to nominate Peter Vaughan for this scene.

 
I'm going to post a bunch of actors nobody else is going to recommend.

John Spencer on West Wing.

 
Matthew McConaughey was regarded as a 2nd rate actor by almost everyone before true detective, which catapulted him up to superstar status. There might be better performances but that one came to mind right away.

Plus his acting in Interstellar and him winning an oscar for Dallas Buyers Club.
 
Has there ever been a more emotional scene in a silly sitcom? Launched a career with that, fresh Willie killed that
That beats out most serious shows in terms of just brutal gut punches.
 
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