Sucralose is a non-caloric sweetener, also known by the trade name Splenda....It is manufactured by the selective chlorination of sucrose, by which three of sucrose's hydroxyl groups are substituted with chlorine atoms to produce 1,6-dichloro-1,6-dideoxy-β-D-fructo-furanosyl 4-chloro-4-deoxy-α-D-galactopyranoside. Unlike aspartame, it is stable under heat and over a broad range of pH conditions, and can be used in baking, or in products that require a long shelf life.
When administered orally, between 11-27% of sucralose is absorbed from the gastrointestinal tract in male humans. The remaining sucralose is excreted in faeces. Following gastrointestinal absorption, between 20-30% of the sucralose is broken down to two metabolites. The remaining sucralose is excreted in urine.
The immunotoxicity of sucralose was assessed in groups of Sprague-Dawley rats (13/sex/group) dosed by gavage with 0-3000 mg/kg bw/day for 28 days. A significant decrease in mean thymus weight was noted in males dosed with 3000 mg/kg bw/day. The NOEL for immunological endpoints was determined to be 750 mg/kg bw/day (USFDA 1998).
Chad Hamilton said:I agree....we cater to all here.
Im in the stratosphere right now and have been for a few months.
Meditation.
No room for science right now.
(I can see you shaking your head Rjkd.)