After completing his chemical studies, Dr. Hofmann chose a position in the pharmaceutical-chemical research laboratory of Sandoz Company in Basel, Switzerland, where he could pursue his interest in studying the medicinal potential of plants. This eventually led to the study of the alkaloids of ergot. A systematic study of the latter led to many interesting new discoveries, some with valuable medical applications, such as Hydergine, a medicament for improvement of peripheral circulation and cerebral function, applied in the control of geriatric disorders and as a "smart pill." Another product was Dihydergot, a circulation and blood pressure stabilizing medicament. Eventually the studies led to the compounding of LSD. No use was found for this compound. But five years later, an intuition led Dr. Hofmann to resynthesize LSD, leading to the famous bicycle ride in April, 1943. The potential of LSD rapidly became apparent.