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I don´t think that is true 100% of the time, at least not if we are talking negative impact. A shitload of factors to consider.
Portugal had a heroin epidemic going and one of the highest pr capita number of addicts. They decriminalized with major success.
That's not a comparison to other legal substances, it's a comparison on the same subject pre- and post- decriminalization.
Decriminalization should not be considered the same as legalization. They are very different in terms of impact. Decriminalizing possession of drugs doesn't change the illegality of mass production and distribution of those drugs. Heroin is still illegal, no company can legally set up a heroin production facility in Portugal and sell it to the public.