Most geniunely motivating/uplifting fighters ever? In no particular order
Kazushi Sakuraba: At a time when the Gracies and BJJ was king, this unknown Japanese pro wrestler who trained in some catch wrestling came and destroyed the entire Gracie family and the belief that BJJ was king. A complete paradigm shift for MMA
Tim Sylvia: A fat, unathletic, 350lb heavyweight who couldn't even jump rope, decided to try his hand at MMA and eventually became champion of the UFC. While he was never close to a fan favorite and was often the butt of many MMA jokes, the guy is the epitome of hard work and making the most of what he has.
Conor McGregor: While is cocky and brash persona may rub many the wrong way, the guy is a genuinely good person and always respectful in victory and defeat. Outside of that, this is a guy who, 5 years ago, was on welfare collecting 188 Euros a month and is now about to get possibly a $100 million pay day. A true self made man, coming from nothing to being the most talked about combat sports athlete in the world.
Michael Bisping: As much as I want to leave Bisping off for being a legit prick and asshole, here is a guy made it all the way to the top after 10 years in the game and when everyone thought he was never anything more than a gate keeper. He continued to grind, to hone his craft and made it. And that's not even mentioning his debilitating eye injury along with having no special skill or natural gift. Not particularly fast nor quick nor athletic but worked hard on honing his overall skills and his cardio. Very inspirational to say the least and a lesson to never give up no matter how many times you fall.
Frankie Edgar: The smallest guy at 155lbs, fights with the heart and fire of a champion and over and over again, over came the odds to be champ. Edgar is the epitome of a fighter who never gives up and just keeps coming, a mini-Terminator.