I've work asics, new balance, Nike, Reebok, tried them ALL while in the army and it always gave me a burning sensation in my joints for the first mile, then numb after that. Later that day I would feel like an old man and I was in my early / mid 20's.
As of two months ago I went with Under Armor, and tried to find a show that had close to a "zero drop" from heel to toe. I figured I had nothing to lose since other shoes with big cushions always hurt my feet.
My first time running I just wanted to go until I got tired, just ran around town aimlessly. After I got home, I looked and I had done 5 miles and never broke a hard sweat or had any joint pain. I expected to have only run 2.
I really recommend the Under Armor Micro G Speed Swifts