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My point though was that a gun in the home is 22 times more likely to be used to kill or injure in a domestic homicide, suicide, or unintentional shooting than to be used in self-defense, and that is an accurate statistic.
Kellermann, Arthur L.MD, MPH, et al. “Injuries and Deaths Due to Firearms in the Home.” Journal of Trauma, Injury, Infection, and Critical Care 45 (1998): 263-67
You've now stated two distinct things as if they were indistinct, and that is misleading. I do not know whether it is unintentional. For what it is worth, the precis of the study you quoted does the same, leading to a very silly conclusion.
First, you made the claim that 22 people are shot by themselves, a friend, or a family member for each person shot in self defense. The numbers of the study in question back this up. Far more people are shot in assaults, homicides, accidents, and attempted or completed suicides than are shot in self-defense. That's here:
And statistically, 22 people were shot by a friend, family member, or themselves for that one instance of a someone being shot in self defense.
Then you said something notably different, which is that a gun is much more likely to be used in a murder, suicide, or accident than used in self-defense. And that is not true nor does the study attempt to prove that, although they sloppily use such language. It's a well-established fact that the vast majority of uses of a gun in self-defense in the US do not involve firing the gun while the study you cited only looked at incidents in which people were injured by guns. So while estimate vary widely, it is a commonly accepted figure that there are about two million defensive uses of handguns annually in the US.
So the conclusion you made here:
a gun in the home is 22 times more likely to be used to kill or injure in a domestic homicide, suicide, or unintentional shooting than to be used in self-defense
is a) false and b) unsupported by the data you provided, which did not track self-defense uses of firearms but only the much narrower category of self-defense shootings.
There was a recent book out, I'll have to find the name, wherein a researcher from Harvard suggested that the uses of guns in crimes not involving shootings is also much higher than reported, because most people use guns to intimidate and threaten far more often than they will use them to murder. So there's plenty of room for discussion on whether guns are a net positive or negative in terms of violent crime. The answer seems to be that it depends on where and when we are discussing, because in most states the crime rate fell as the amount of gun ownership and legal concealed carry licenses rose. But in some states like Illinois the murder rate shot up as guns became more available. Its a complicated discussion, and conflating different things like self-defense usage of guns with self-defense shootings is unhelpful and confusing.