Only loot boxes I opened I got from avenging some other dudes being killed in the game. Pretty much reaching the end of the main story. Afterwards is a PLANNED long term after story grind where you run around beating up orcs and defending shit. Just like any MP game. Like grinding your way to 100% in any way. Except chopping off heads and training orcs is a lot more fun than the shit you normally do. So NOPE microtransactions have zero affect on normal game play. They give you zero fucking advantage in single play. You cannot and do not need pay to win or even avoid a grind in normal play.