Two referendums, both voted no. Separation still exists as a dream here for some (mainly the older generation that lived through the quiet revolution), but it's pretty much widely acknowledged now that it'll never happen (especially after the last embarrassing run the PQ had as provincial government). The old guard may try to position the transfer payments as a guarantee QC won't leave the confederation, but it's an empty threat. Montreal, immigrants and Anglo population basically ensure that QC will stay part of the confederation.
The problem is that Quebec is addicted to the luxuries these transfer payments provide and not surprisingly, they don't want to give them up. Take the student protests 5 years ago for example. There was a very modest and reasonable proposal to raise tuition, which is by far the lowest in the country, probably the lowest in N. America, all tax payer subsidized. IIRC it was something like a $350 annual hike for the next 7 years which would still only barely bring it in line with the rest of Canada. Students were having none of it, so they protested and got what they wanted. Interesting to add that the only university in Quebec that didn't participate was McGill, which is also the only notable school here (Concordia being the distant second). So we can rest assured that all the Arts majors at the provincial shit schools still get to discover themselves through education, provided at basement budget rates, sponsored by the rest of Canada.
The same thing happened with the cops who were protesting budget cuts for years by wearing non-uniform cargo pants. To put that into perspective, it's very common here in Montreal to see a cop work the traffic lights. They are not directing traffic, they are literally pressing a button to change the traffic lights. All. Day. Long. I see it several times on my way to work, and I only have a 20 minute commute. I bring this up because it demonstrates the inefficiency and petulance of government workers here: Why in the fuck are we using someone who makes 70K/year to change fucking traffic lights? That's a $20 an hour job maximum. Better yet, why don't these fucking traffic lights just do what they're supposed to do? How hard is it to get that fixed???
Or take a look at where government offices are located. Why in the living fuck would you put a government office in the old port, right next to the canal, one of Montreal's most expensive areas? You're a government worker, put that shit in an industrial park somewhere. It's good enough for private businesses, it's good enough for public administrations.
I already brought up other deficiencies, like the complete lack of government services streamlining. Lost your health card? No problem, you can get a new one on-line. There'll be approximately 38 steps to follow, one of which will involve your old health care card. Yep, the one you need to replace...because you lost it. Makes sense? No lol, ofc not, but this is Quebec. Did you move here from another provinces and need to transfer your driver's license? Yea, you're gonna have to make an appointment at one of the two offices in Montreal (pop. 3.5 million) that are actually equipped to do this. It'll take 6 weeks to get the appointment, and you will need to bring a mountain of paperwork, for example, 6 months of original bills to prove that you lived in the very province your current driver's license is from. You do online billing? Don't think you can simply print out the bills, you need originals. The whole process literally takes at least 8 hours of running around, and most people don't even make it on the first try because they failed to satisfy one of the ridiculous bureaucratic requirements.
The rest of Canada needs to call the bluff, Quebec isn't going anywhere, and the provincial government structure needs a complete overhaul and needs to integrate with the federal government like the rest of the provinces (fun fact: During tax season I get to spend twice as much time doing taxes, because on top of my T4 I also have a Releve 1, Quebec's own version of the T4. Why? Because fuck me, that's why).