Hey Jones! Viagra Increases Muscle Protein Synthesis and Reduces Muscle Fatigue

[Washad]

I'ma throw some science your way now....

Notably, the approximate doubling of skeletal muscle protein synthesis observed in response to sildenafil is of similar magnitude to that observed in response to 100–200 mg/week testosterone injection, an intervention which increases skeletal muscle mass and strength but does not reduce muscle fatigability with long‐term administration.

Reductions in skeletal muscle function occur during the course of healthy aging as well as with bed rest or diverse diseases such as cancer, muscular dystrophy, and heart failure. However, there are no accepted pharmacologic therapies to improve impaired skeletal muscle function. Nitric oxide may influence skeletal muscle function through effects on excitation‐contraction coupling, myofibrillar function, perfusion, and metabolism. Here we show that augmentation of nitric oxide‐cyclic guanosine monophosphate signaling by short‐term daily administration of the phosphodiesterase 5 inhibitor sildenafil increases protein synthesis, alters protein expression and nitrosylation, and reduces fatigue in human skeletal muscle. These findings suggest that phosphodiesterase 5 inhibitors represent viable pharmacologic interventions to improve muscle function.

The full study:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076819/

TL;DR Dick Pill Jones is cheating even with his made-up excuse.

Jason Parillos take on it:

 

[Unheralded Truth]

 

[Brock-B-level-Athlete]

 

[Reign009]

Jones took some enhancement so he could fook but he's the one getting fooked by USADA.

 

[Hotora86]

Is Viagra a PED then?

 

[Canada]

Let’s enjoy this thread and point at the cheater.

We all know deep in our hearts that he is the best to ever do it.

 

[OlderMan]

I'ma throw some science your way now....





The full study:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076819/

TL;DR Dick Pill Jones is cheating even with his made-up excuse.

Jason Parillos take on it:

great post

 

[OlderMan]

Is Viagra a PED then?

duhhhhhhhhhhhh!

in more ways than one.....

Why use IF you don't need it? Who needs a supercharger on their Corvette........ ?.. Twin turbos on their Diesel Truck?

Been there done that ...V that is. and C.

HOT DAMN...

This old mustang Gt Ran like a new Rousch Mustang...

Just sayin....

 

[Mbmmax]

Let’s enjoy this thread and point at the cheater.

We all know deep in our hearts that he is the best to ever do it.

Just like Bonds is the greatest baseball player ever and Armstrong the greatest cyclist?

 

[ortizgnp]

Just like Bonds is the greatest baseball player ever and Armstrong the greatest cyclist?

If you knew anything you'd know that Armstrong in fact is considered the greatest by people in the industry. Look at who he competed against, for christs sake.

I don't watch baseball.

 

[Gorkle]

Just like Bonds is the greatest baseball player ever and Armstrong the greatest cyclist?

Bonds is one of maybe 3 baseball players anyone from outside the US could actually name. So by default he's number 3 at least.

Same with Armstrong.

 

[Charnel2500]

Anderdon Silva approves

 

[NoAbsolutes]

Bonds is one of maybe 3 baseball players anyone from outside the US could actually name. So by default he's number 3 at least.

Same with Armstrong.

Fame and skill are two different things.

 

[Yashabo]

Bonds is one of maybe 3 baseball players anyone from outside the US could actually name. So by default he's number 3 at least.

Same with Armstrong.

I've never heard of Bonds. And Armstrong is a disgrace.

 

[HelpYouFall]

If you knew anything you'd know that Armstrong in fact is considered the greatest by people in the industry

Not really. By and large, Eddy Merckx is considered the greatest cyclist of all time and it's not even close.

 

[ortizgnp]

Not really. By and large, Eddy Merckx is considered the greatest cyclist of all time and it's not even close.

Never heard of him

 

[Gorkle]

I've never heard of Bonds. And Armstrong is a disgrace.

How many baseball players can you name though? I can literally think of 3.

Of course Armstrong is a disgrace, however a large amount of this was just the fact he was the one who won. Every other bastard there was doing the exact same thing. He excelled in a sport against his peers who more or less had the same unfair advantage he had.

 

[trident]

If you knew anything you'd know that Armstrong in fact is considered the greatest by people in the industry. Look at who he competed against, for christs sake.

I don't watch baseball.

I can confirm. Lance is GOAT

 

[trident]

I've never heard of Bonds. And Armstrong is a disgrace.

As long as you are sure to throw in the entire front half of the peloton into that disgrace comment self righteous jerk

 

[TheScorpionDude]

I'ma throw some science your way now....





The full study:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076819/

TL;DR Dick Pill Jones is cheating even with his made-up excuse.

Jason Parillos take on it:

You're telling him !? Jones probably has a PhD in steroids by now. He's done the research, and the experiments.